"When killing cancer cells, it also kills normal cells." This puzzle that puzzles doctors and cancer patients around the world is finally expected to be cracked. The author learned from Sun Yat-sen University on the 13th that Yan Guangmei, a professor at Zhongshan Medical College of Sun Yat-sen University, published a natural disease on the 7th in the international journal The Academy of Sciences.

Release date: 2014-10-14

"When killing cancer cells, it also kills normal cells." This puzzle that puzzles doctors and cancer patients around the world is finally expected to be cracked. The author learned from Sun Yat-sen University on the 13th that Yan Guangmei, a professor at Zhongshan Medical College of Sun Yat-sen University, published a new study on the selective anti-tumor effect of natural alphavirus M1 on the 7th in the international journal The Academy of Sciences. A natural virus called M1 can specifically kill cancer cells without harming normal cells. This new oncolytic virus is expected to become a new generation of anti-cancer weapon.

The research results were independently completed by Yan Guangmei, a professor at Zhongshan University School of Medicine, and had complete independent intellectual property rights. Lin Yuan, Zhang Haipeng and Liang Jiankai were co-first authors. Paper link

The global cancer incidence rate is growing rapidly, and the existing treatment methods are far from meeting the clinical needs. After many years of research, Yan Guangmei's research team isolated a natural virus of M1 from Hainan Island. The Yan Guangmei team used cell culture methods to find that the M1 virus selectively infects and kills a variety of cancer cells including liver cancer, colorectal cancer, bladder cancer, melanoma, and has no toxic side effects on normal cells. The overall animal model demonstrates that the M1 virus “finds and destroys tumor tissue as accurately as the eye grows” and normal cells are unaffected.

In addition to cell levels and animal experiments, the team further confirmed the efficacy and specificity of the above new oncolytic viruses using clinical specimens in vitro tissue culture models.

According to reports, more importantly, the research work also proves the molecular genetic mechanism of the role of M1 virus. This discovery provides a reliable scientific basis for accurate clinical medication and individualized therapy, and greatly increases the number of future clinical trials. The chance of success. According to experts, the new natural oncolytic virus M1 will safely and effectively treat cancer, and is expected to become a new generation of tools to overcome human cancer.

Source: Nanfang Daily

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