Release date: 2016-08-04

Recently, researchers have developed a new type of tumor treatment device that can simultaneously release three different types of drugs to achieve a specific tumor attack.

So far this technique has only been validated at the mouse level, but because the results are very satisfactory, the researchers believe that this new type of adhesive can effectively treat colon cancer.

To date, the most important aspect of the treatment of colon cancer patients is surgical removal of the tumor mass. But it is still impossible to completely remove cancer cells. This is the meaning of this new type of sticker.

This technique is primarily designed for the treatment of residual tumor masses after surgery. "We hope to use the technical means of materials science, especially nanotechnology, to treat local tumor residues." The lead author of the study, Natalie Artz from the MIT Medical Engineering Science Institute, said.

The results of this adhesive in animal experiments are satisfactory, and the device begins to effectively remove tumor tissue even before surgical removal of the tumor. In the trial of surgical resection, there was no case of tumor recurrence after using this sticker!

In principle, this sticker achieves the goal of killing tumor tissue in three ways. First, it releases tiny gold nanoparticles that cause high temperatures to destroy the tumor; after that, the high temperature environment releases the chemical in the gold particles for further killing; finally, the core of the gold particles can carry small RNA molecules. It reaches the inside of the tumor tissue and inhibits the canceration of normal cells by RNA silencing.

Researchers believe that this sticker can be used both before and after surgery, and that the tape will naturally degrade as it is heated by the patient's body temperature.

Colon cancer is the second most common type of cancer in the United States and one of the most common cancers. One million people worldwide are diagnosed with colon cancer each year. The next step for researchers is to test the reliability and effectiveness of this new technology on large animals, and if the results are still satisfactory, they will consider clinical trials.

The results were published in the journal Nature Materials.

Source: Bio Valley

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