Sheep organophosphorus pesticide poisoning is a toxic pathological process caused by contact, inhalation or intake of organophosphorus preparations in sheep, which is characterized by the inhibition of cholinesterase activity in the body and leading to neurophysiological disorders.

Experts solve the disease. (1) Etiology: Organophosphorus pesticides are common insecticides in agriculture, and they are also insecticides and anthelmintics commonly used in animal husbandry. There are mainly phosphorus (3911), parathion (1605), phosphorus uptake (1059), dimethoate, trichlorfon and so on. Most of these insecticides are highly fat-soluble and can permeate into the body through the skin and are absorbed more quickly through the digestive tract and respiratory tract. Sheep organophosphorus poisoning is often eaten grass or crops, vegetables, etc. that are sprayed with organophosphorus pesticides; eating water that is contaminated with organophosphorus pesticides; eating seeds that have been mixed with pesticides; and using organic phosphorus pesticides to control ectoparasites in sheep. Excessive doses or improper use; sheep exposed to various organophosphorus pesticide contaminated equipment utensils, etc., and poisoning occurred.

(2) Symptoms: Organophosphorus poisoning can be clinically divided into three types of syndromes: a, muscarinic symptoms: manifested as loss of appetite, runny nose, vomiting, diarrhea, abdominal pain, sweating, urinary incontinence, miosis, visible pale mucous membranes , dyspnea, pulmonary edema, and cyanosis; b, nicotine-like symptoms: manifestations of muscle fibrillation, blood pressure, pulse frequency, paralysis; c, central nervous system symptoms: manifestations of excitement, elevated body temperature, convulsions , Drowsiness, etc., poisoned sheep excited, jumped and jumped, tremors, gradually gait instability, and even fell to the ground, suffocating under paralysis died.

(3) Diagnosis: Diagnosis can be based on symptoms, toxic exposure history, toxicological analysis, and determination of cholinesterase activity.

Expert treatment. 1Prevention: a. Strict pesticide management systems and methods of use are not grazing in areas where pesticides are being sprayed, and seeds that have been mixed with pesticides must not be fed to sheep. b. Salt is an important feed ingredient, but if it is eaten too much or fed improperly, it will cause livestock poisoning. c. The amount of poisoning caused by sheep was 3 g/kg body weight.

2 treatment: a, gavage salt laxatives, as soon as possible to remove stomach poisons, magnesium sulfate or sodium sulfate can be used 30-40 grams, water once appropriate amount of oral administration; b, application of special antidote, available pralidoxime, chlorine phosphorus, According to 15-30 mg per kilogram of body weight, it is dissolved in 100 ml of 5% glucose solution and injected intravenously. After every 2-3 hours, the dose is halved. Repeated injection can be repeated within 48 hours according to the symptomatic relief. Double-decomposition phosphorus, double-recombinant phosphorus, the dose of half of pralidoxime, the same usage; or with atropine sulfate, 10-30 mg per kilogram of body weight, intramuscular injection. Symptoms are not alleviated. Phosphoridine and atropine sulfate can be used repeatedly.

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