Release date: 2013-03-06

Xinhua News Agency, Los Angeles, March 3 - US researchers reported on the 3rd that they achieved the first "functional cure" for HIV-infected infants through antiretroviral therapy. Researchers at the Johns Hopkins Children's Medical Center and the University of Mississippi reported at the 2013 Conference on Retroviruses and Opportunistic Infections in Atlanta, USA, that they selected one of them two years ago. Infants infected with HIV through mother-to-child transmission are treated. After the baby was born 30 hours later, the researchers performed combined antiretroviral therapy. The test proved that the amount of HIV in the blood of the baby girl was significantly reduced after treatment, and the HIV in the body was not detected after 29 days of birth. The researchers continued to receive antiretroviral therapy for her within the next 18 months, and after 10 months of cessation of treatment, the HIV antibody was still negative in the body, and no HIV was found in routine blood tests. The researchers said: "Antiretroviral treatment of neonates can prevent HIV-infected host cells from hiding in the body. This treatment can clear and inhibit the virus and achieve a 'functional cure' in the absence of lifelong treatment." "Functional cure" means that the HIV in the infected person is completely inhibited, and the body's immune function is normal. Even if it is not treated, it is difficult to detect the virus in the blood of the child by conventional methods. Researchers say that eradicating HIV, the "fundamental cure" of AIDS, is currently difficult to achieve. Drug treatment for HIV-infected people now generally begins between 3 and 4 months after birth, so early and accurate antiretroviral therapy is important for HIV-infected babies. According to reports, there are currently about 2.5 million babies infected with HIV in the world, and about 1700 new cases of mother-to-child transmission of HIV every day. (Source: Xinhua News Agency)


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