In 2005, the County Grassland Station of the county had introduced 220-month old New Zealand breeder rabbits from a county outside the county for the purpose of implementing the project of raising grass and raising livestock. The animals were distributed to ten households in Tongtong and Changchong villages in Carol Township. Farmer farming. On the second day after the rabbits were released, animal husbandry technicians went to each farmer to provide technical guidance for breeding and all rabbits were injected with rabbit Blastococcus pastoris. On the third day, the farmer reported that 2 rabbits died. At that time, we thought that it was an individual stress reaction that the rabbit may have due to transportation and environmental changes. It did not attract attention. It just explained to the farmers to strengthen the feeding management and pay attention to the health of the rabbit house. Add ciprofloxacin to drinking water for prevention. However, on the fourth and fifth days, rabbits were still dying one after another, 5-8 deaths per day, and more than 10 deaths. We went to the hospital for treatment. 1 Clinical symptoms and pathological changes According to farmers' presentations and clinical examinations, most of the symptoms were sudden death, and no obvious symptoms appeared before death. The main manifestations of a relatively long course of disease were lack of energy, decreased intake or no eating, fecal fines, and death 1 to 2 days later. At the necropsy of two dead rabbits, the main change was that the stomach was full of fluids and gases, there was a small amount of bleeding in one lung, and no obvious abnormalities were seen in other organs. 2 Diagnosis and treatment At that time, we failed to diagnose the cause of the disease and we treated it with pasterellosis. We used blue and streptomycin in an intramuscular injection of 10,000 IU per kilogram of body weight. We also used sulfadiazine to feed 0.2 g per kilogram of body weight in the feed. . However, there is no therapeutic effect and rabbits continue to die. In order to obtain a clear diagnosis and effective treatment, we collected medical materials and sent them to the Department of Animal Science of Guizhou University for laboratory tests. Through isolation and culture and biochemical tests (test reports are omitted), the final diagnosis was E. coli. Drug susceptibility test results showed that the strain was insensitive to penicillin, streptomycin, ciprofloxacin, doxycycline and sensitive to norfloxacin and furazolidone. According to the results of laboratory tests and drug susceptibility tests, we have adopted appropriate prevention and control measures: (1) Isolation therapy for rabbits, fed with norfloxacin, and 4 g per kilogram of body weight in feed, plus 1 g per liter of water. (2) All the farmers are required to clean and disinfect the rabbit house and replace the litter. (3) Healthy rabbits were fed with 1 g of norfloxacin per liter of water for 3 days in drinking water. After the above treatment, all rabbits were cured. 3 Summary and Experience (1) The E. coli infected by this group of rabbits may be brought from the feeding unit and induced by stress factors. Therefore, special attention should be paid to the feeding and management of breeding units and the health status of rabbits when introduced. . (2) Because of the backwardness of diagnostic methods, grass-roots units should promptly send inspections to relevant departments when they cannot make a diagnosis, so that effective treatment measures can be taken as soon as possible to reduce losses. (3) E. coli disease is a common bacterial disease in rabbits. Due to bacterial variation and the increase in the amount of veterinary drugs used in recent years, some strains have a certain degree of drug resistance. Different strains have different susceptibility to drugs. Therefore, it is advisable to carry out drug susceptibility tests and use targeted drugs to achieve the best results. Small Starch Separator Machine Small Starch Separator Machine,Industrial Starch Production,Starch Separator Machine,Starch Vibration Separator Machine Shuangfeng County Dingyuan Machinery Manufacturing Co. Ltd.. , https://www.separators.pl