Release date: 2016-11-16 The organic electronic ion pump has six small holes (black dots on the gold squares) that release the neurotransmitters at high speed. To compare the size, we placed this ion pump next to a Swedish coin (about 1 cent coin size). Human neurons transmit information 30 times faster than our blinks. A neuron releases the chemical through the cell membrane within 10 milliseconds, and the receptor is then received by the receptor on the adjacent cell, and the information is transmitted. So far, even under the influence of microfluidics, researchers have not been able to simulate high-speed chemical signals. Currently, Sweden Link? A team at Ping University has designed and created an electronically controlled ion pump that delivers neurotransmitters at a rate comparable to that of living neurons. This new instrument is an improved version based on the old version of the Organic Electron Ion Pump (OEIP) developed by the same laboratory. This instrument relies on an electric field to cause charged particles to pass through the membrane without any fluid. The 2.5 cm pump is made of metal and the polymer channel is printed onto the glass by photolithography and connected to a power source. Traditional instruments move ions from the ion source horizontally along the channel to the target area. These ions can be any small charged particles such as neurotransmitters, protons, and metal ions. The lateral motion described above is relatively slow, sometimes taking several seconds from powering up to reaching the target. However, this newly developed pump takes advantage of the ultra-thin characteristics of polymer films and achieves its purpose through longitudinal movement. “We didn't use a film that traversed a few millimeters in the transverse direction, but instead used the longitudinal thickness of the same film, only a few hundred nanometers in the longitudinal direction.†Research team member Daniel Simon said that he is also a Link? Ping Assistant Professor at the University's Organic Electronics Laboratory. It works like this: The current pushes the neurotransmitter along six horizontal paths, with a small hole in the middle of each path. When the switch is turned on, the researchers activate the electric field that changes the ion source and quickly direct the charged particles along the short vertical channel to the small hole. . The researchers then set a target for them, such as a cell or a piece of tissue. The team started with the acetylcholine test instrument, a common neurotransmitter in the brain and motor neuron connections that allows chemicals to reach the target within 45 to 50 milliseconds. These six new high-speed aligned ion delivery channels can be activated separately, allowing researchers to freely transfer neurotransmitters to any part of the sample. Therefore, they were able to activate a group of neurons in the culture dish with acetylcholine without destroying other neurons. Currently the team is testing instruments on living cells, in addition to improving our ability to study neuronal signals, this technology can also open the door to the development of brain transplantation for high-speed delivery of neurotransmitters. In the future, this ion pump may also be combined with chemotherapy for today's brain electrical stimulation therapy, such as deep stimulation of the brain to treat epilepsy, Simon said, "to treat neurodegenerative diseases through compounds that the body does not normally produce signals. Unlimited opportunities for development." Source: Lei Feng Net China Extract Powder For Use As Dietary Supplement Extract Powder, Extract Powder Manufacturer Shaanxi Kang New Pharmaceutical co., Ltd. , https://www.apipepdites.com