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Microbial fertilizer refers to a bioactive fertilizer that contains living microorganisms to produce fertilizer effects through their life activities and promote the growth of crops. In the past more than 10 years, the development of bio-fertilizer has been rapid. Many companies have turned to invest in bio-fertilizer and new products have been introduced. More than 300 products have been registered temporarily across the country. Efficient bio-fertilizer is a new type of bio-fertilizer developed by the Institute of Plant Ecological Engineering of China Agricultural University according to the principle of plant microecology. It is also a kind of plant health-care preparation. It is a variety of microorganisms mainly endophytic Bacillus spp. After a special fermentation process prepared. II. The product performance mainly has the following four characteristics: (1) High-efficiency multi-functionality: It has functions of promoting crop growth, increasing yield, improving quality, and improving stress resistance. (2) Extensive adaptability: less affected by geographical and environmental conditions. (3) Great affinity: colonization and transfer in plant body surface and body. (4) High degree of safety: It is non-toxic and non-polluting to plants, animals, and the environment. III. Application Scope and Popularization and Application At present, various special types have been successfully developed for different crops, such as special rice and wheat, vegetable-specific, cotton-specific, soybean-specific, rapeseed-specific, beet-specific, orchard-specific. Type more than 20 varieties. Generally used for monocotyledonous plants to increase production by 10%-15%, dicotyledonous plants increase production by 15%-20%, at the same time can improve product quality and enhance resistance to diseases, adverse environments. IV. Analysis of market prospects As the destruction of soil and environment by chemical fertilizers has received increasing attention, the effect of using biological fertilizers has gradually been recognized by farmers. The application area has been expanding and a small number of products have begun to enter the international market. In addition, the national planting structure has been adjusted from the previous pursuit of production to the development of fine agricultural products (good quality, no pollution, etc.), undoubtedly has an important role in promoting the development of biological fertilizers, and the demand for biological fertilizers is also growing.