Expectorants Powder Ambroxol Hydrochloride CAS 23828-92-4

Basic information
CAS No:23828-92-4                                                                        Einecs No.: N/A
Character:White  powder                                                              MF: C14H21Br2ClN2
MW:414.56376                                                                                 Purity:99%
Quality Guarantee Period:Two Years Min                                   Grade Standard:enterprise standard
Sample:10-20g Free Sample                                                          Brand Name:Wongpharm

Ambroxol hcl CAS 23828-92-4

Molecular formula:23828-92-4  
Molecular weight: 414.56376        
Character:White  powder        

 

Ambroxol hydrochloride is a small molecule expectorant and mucolytic agent with antioxidant and antiinflammatory effects. Ambroxol stimulates the secretion of surfactant which decreases mucus adhesion to the bronchial lining and produces expectorant effects. The antioxidant effects of Ambroxol are well demonstrated, where lipid peroxidation initiated by t-butyl hydroperoxide or doxorubicin is suppressed in the presence Ambroxol, and scavenging of hydroxyl radicals and cellular superoxide radical anions is also observed. Ambroxol produces antiinflammatory effects by blocking the expression of proinflammatory messengers, inhibiting the release of histamine from mast cells and the generation of cytokines and interleukins. Ambroxol hydrochloride is an inhibitor of Sodium Channel Protein.

Main use:
Expectorant has good mucolysis effect and lubricating respiratory tract effect. It can promote the secretion of pulmonary surfactant, respiratory fluid secretion and cilia movement, etc. It is used in the treatment of acute and chronic respiratory diseases, abnormal bronchial secretion and so on.

Pharmacological toxicology:
This product has the characteristics of mucus exclusion, promotion and dissolution of secretions. It can promote the removal of viscous secretions from the respiratory tract and reduce the retention of mucus, thus significantly promoting the discharge of phlegm and improving the respiratory status. The secretion of mucus returns to normal. Coughing and sputum volume are usually significantly reduced, and the surfactant on the mucous membrane of the respiratory tract thus performs its normal protective function.

Pharmacokinetics:
The half-life was 7-12 hours, no accumulation was found, and 90% of the liver metabolites were cleared by the kidney.

Indication:
For acute, chronic respiratory diseases with abnormal sputum secretion and poor sputum function, such as acute exacerbation of chronic bronchitis, asthmatic bronchitis, and expectorant treatment of bronchial asthma;


Quality standard: enterprise standard
Content: ≥ 98.0%
Package:25kg/drum

 

specification

 

Basic information
CAS No:23828-92-4                                                                        Einecs No.: N/A
Character:White  powder                                                              MF: C14H21Br2ClN2
MW:414.56376                                                                                 Purity:99%
Quality Guarantee Period:Two Years Min                                   Grade Standard:enterprise standard
Sample:10-20g Free Sample                                                          Brand Name:Wongpharm

Ambroxol hcl CAS 23828-92-4

Molecular formula:23828-92-4  
Molecular weight: 414.56376        
Character:White  powder        

 

Ambroxol hydrochloride is a small molecule expectorant and mucolytic agent with antioxidant and antiinflammatory effects. Ambroxol stimulates the secretion of surfactant which decreases mucus adhesion to the bronchial lining and produces expectorant effects. The antioxidant effects of Ambroxol are well demonstrated, where lipid peroxidation initiated by t-butyl hydroperoxide or doxorubicin is suppressed in the presence Ambroxol, and scavenging of hydroxyl radicals and cellular superoxide radical anions is also observed. Ambroxol produces antiinflammatory effects by blocking the expression of proinflammatory messengers, inhibiting the release of histamine from mast cells and the generation of cytokines and interleukins. Ambroxol hydrochloride is an inhibitor of Sodium Channel Protein.

Main use:
Expectorant has good mucolysis effect and lubricating respiratory tract effect. It can promote the secretion of pulmonary surfactant, respiratory fluid secretion and cilia movement, etc. It is used in the treatment of acute and chronic respiratory diseases, abnormal bronchial secretion and so on.

Pharmacological toxicology:
This product has the characteristics of mucus exclusion, promotion and dissolution of secretions. It can promote the removal of viscous secretions from the respiratory tract and reduce the retention of mucus, thus significantly promoting the discharge of phlegm and improving the respiratory status. The secretion of mucus returns to normal. Coughing and sputum volume are usually significantly reduced, and the surfactant on the mucous membrane of the respiratory tract thus performs its normal protective function.

Pharmacokinetics:
The half-life was 7-12 hours, no accumulation was found, and 90% of the liver metabolites were cleared by the kidney.

Indication:
For acute, chronic respiratory diseases with abnormal sputum secretion and poor sputum function, such as acute exacerbation of chronic bronchitis, asthmatic bronchitis, and expectorant treatment of bronchial asthma;


Quality standard: enterprise standard
Content: ≥ 98.0%
Package:25kg/drum

 

specification

 

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