According to relevant national agencies, except for the high temperatures in most of the northeast and north China, the temperature in most other regions was lower than usual during the spring. The western part of Xinjiang, the southeast part of the northwest, the Sichuan Basin, the south of the south of the Yangtze River and the east of the South China were about 1 degree Celsius lower. Most of southern China and southern China may experience cold weather. In March, the temperatures in most parts of southern China, southern China, most of the southwest, the Qinghai-Tibet Plateau, and southern Xinjiang were lower than usual, with southeastern Sichuan and northwestern Guizhou being around 1 degree Celsius lower than usual. Based on this, it is inferred that cold damage and early flowering are most likely to occur on tobacco in the above areas, especially the occurrence of cold damage and early flowering in the southwestern northwest, the Sichuan Basin, southern Jiangnan, and eastern South China. In addition, due to the constraints of environmental conditions and cultivation systems, the occurrence of cold damage and early flowering in the early spring in spring tobacco in the northern region is very common. Please also pay attention to prevention. 1. Cold damage and early flowering The greatest danger of cold damage is early flowering, which can also be caused by freezing when the temperature is particularly low. The main factor leading to early flowering is low temperature. The prolonged low temperature (13-18°C, 2-3 weeks) in tobacco seedling stage and early field stage can easily cause early flowering. The main physiological mechanism is the promotion of flower bud differentiation at low temperature. There are differences in the sensitivity of tobacco varieties to low temperatures, and some varieties are prone to early flowering. It has been observed that foreign varieties, especially G80 and NC82, are particularly sensitive to low temperatures and are prone to early flowering; Heilongjiang Survey, NC89, Longjiang 85-1, K346, K326, etc. have a great chance of early flowering. In the formulation of prevention and control measures should focus on prevention of sensitive species. (1) Timely transplanting, pay attention to the insulation measures in the late seedbed stage and in the early days of Daejeon. (2) Plastic film covering in the tobacco field earlier transplanting period can effectively prevent the occurrence of early flowers. 2 Rescue measures after early flowering The main manifestations of early flowering tobacco plants are: early bud emergence, reduced number of leaves per plant, and weak growth. Responsible rescue measures should be taken for the above performance to reduce losses. Generally take smoke cultivation and strengthen fertilizer and water management measures. The specific measures are as follows: early after the phenomenon of early flowering, topping more than normal to hit 2 leaves (commonly known as the low topping), in order to facilitate bud sprouting long, axillary bud germination, choose to stay strong buds, The rest was erased, and the position of the so-called haze was better at the leaves of the 2-3 leaves from the parietal lobe (commonly known as the eel). The number of leaves should be equal to or slightly less than that of normal tobacco leaves. Before and after the budding, we must seize the time to top-dressing, watering, soil, soil should be higher than the normal soil (commonly known as high soil). (This method is also suitable for remedial measures when severe damage is caused by hail in the middle of Daejeon.) Early flowering tobacco plants are very weak, and special attention should be paid to the principle of preferring rather light, rather not too late, if the topping is too light or Too late, not only the main stem smoke can not be opened, but also the growth of smoke is also affected, can not play its due role. Generally, every leaf of the main stem smokes more than one leaf, and the length of the smoke can be 2-3 leaves.

Our factory mainly produces various anticancer active pharmaceutical ingredients (API) and their intermediates, most of which meet the USP/EP/JP standard.At the same time, we maintain long-term and close cooperation with many research institutions and universities, Our co-production plants are located in Anhui, Jiangsu, Zhejiang and Inner Mongolia. Our major products are antineoplastic, cardiovascular and antibiotics and their intermediates.

Our major anticancer products are Sorofenib, Sunitinib, Axitinib, Ibrutinib, Enzalutamide, Vemurafenib, Lenvatinib, Decitabine, Venetoclax and their intermediates. 

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APIs And Intermediates

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